蛋白质的疏水性怎么预测

来源:学生作业帮助网 编辑:作业帮 时间:2024/04/28 06:14:54
蛋白质的疏水性怎么预测

蛋白质的疏水性怎么预测
蛋白质的疏水性怎么预测

蛋白质的疏水性怎么预测
根据氨基酸的序列以及折叠的空间结构预测吧
蛋白质生物信息学工具
One of the most used sites for obtaining sequence data and using it to compute various physicochemical properties of proteins is the ProtParam feature of ExPASy (Expert Protein Analysis Software)Web site (http://www.expasy.org/tools/protparam). ProtParam calculates many of the protein parameters including MW, theoretical pI, amino acid composition, atomic composition, extinction coefficient, estimated half-life, instability index, aliphatic index, and grand average of hydropathicity (Gasteiger et al., 2005).
使用最多的网站之一是ExPASy(Expert Protein Analysis Software)网站中的ProtParam部分 (http://www.expasy.org/tools/protparam),用它可以得到蛋白质的序列数据,还可以计算蛋白质各种各样的理化性质.ProtParam能够计算的蛋白质参数有:分子量MW,等电点pI,氨基酸组成,原子组成,消光系数,估算半衰期,不稳定性系数,脂溶指数和总平均亲水性.